PhD fellowship in Functional Genetics at BRIC

Profilbillede
dato

BEMÆRK: Ansøgningsfristen er overskredet

Faculty of Health and Medical Sciences
University of Copenhagen


We are offering a PhD fellowship in Functional Genetics commencing 1 July 2023.

Our group and research
The overarching goal of my research is to understand mechanisms underlying maintenance of genome stability in mammalian cells, and how impairments of these mechanisms cause diseases such as familial breast cancer. Based on this foundational understanding, we aim to find new targets for cancer therapy as well as improve current therapies. We are a group of approx. 12 researchers that work in close contact with clinical collaborators.

Project description
The PhD student will unravel new functions of the major tumor suppressor BRCA2. The first aim of this project is to decode the role of BRCA2 cancer-associated variants with focus on the C-terminus using our newly developed CRISPR-Select variant functional assay. This assay is unique as it allows quantitative estimate of variant impact on protein function. Additionally, we have uncovered a new C-terminal interaction partner for BRCA2, and the student will investigate how this factor regulates BRCA2 function.

Principal supervisor is Professor Claus Storgaard Sørensen, BRIC. For information contact him on e-mail: claus.storgaard@bric.ku.dk

Start: 1 July 2023

Duration: 3 years as a PhD student

Job description
Your key tasks as a PhD student at SUND are:

  • Carrying through an independent research project under supervision.
  • Completing PhD courses or other equivalent education corresponding to approximately 30 ECTS points.
  • Participating in active research environments including a stay at another research team.
  • Obtaining experience with teaching or other types of dissemination related to your PhD project
  • Teaching and disseminating your knowledge.
  • Writing a PhD thesis on the grounds of your project
Key criteria for the assessment of applicants
Applicants must have qualifications corresponding to a master’s degree related to the subject area of the project, e.g. functional genetic research in human cell lines. Please note that your master’s degree must be equivalent to a Danish master’s degree (two years).

Other important criteria are:

  • The grade point average achieved
  • Professional qualifications relevant to the PhD project
  • Previous publications
  • Relevant work experience
  • Other professional activities
  • A curious mind-set with a strong interest in cancer and functional genetics.
  • Language skills
Place of employment
The place of employment is at BRIC, Faculty of Health and Medical Sciences, University of Copenhagen. We offer creative and stimulating working conditions in dynamic and international research environment. Our research facilities include modern laboratories and a number of core facilities shared between the 23 research groups at BRIC and the neighboring Finsen Laboratory. The Sørensen team has weekly journal clubs and data clubs. BRIC runs seminars with invited speakers, a young researchers club ASAP and our own PhD programme, MoMeD and our own Postdoc Career Programme. Please read more about the Sørensen research group and BRIC on http://www.bric.ku.dk/

Terms of employment
The average weekly working hours are 37 hours per week.
The position is a fixed-term position limited to a period of 3 years. The start date is 1 July 2023.
The employment is conditioned upon the applicant’s success­ful enrolment as a PhD student at the Graduate School at the Faculty of Health and Medical Sciences, University of Copenhagen. This requires submission and acceptance of an application for the specific project formulated by the applicant.
The PhD study must be completed in accordance with The Ministerial Order on the PhD programme (2013) and the Faculty’s rules on achieving the degree.

Salary, pension and terms of employment are in accordance with the agree­ment between the Ministry of Taxation and The Danish Confederation of Professional Associations on Academics in the State. Depending on seniority, the monthly salary starts at approximately 28,800 DKK/Roughly 3,800 EUR (April 2023 level) plus pension.

Questions
For specific information about the PhD fellowship, please contact the principal supervisor.

General information about PhD studies at the Faculty of Health and Medical Sciences is available at the Graduate School’s website: https://healthsciences.ku.dk/phd/guidelines/

Application procedure
Your application must be submitted electronically by clicking ‘Apply now’ below. The application must include the following documents in PDF format:

1. Motivated letter of application (max. one page)
2. CV incl. education, experience, language skills and other skills relevant for the position
3. Certified copy of original Master of Science diploma and transcript of records in the original language, including an authorized English translation if issued in other language than English or Danish. If not completed, a certified/signed copy of a recent transcript of records or a written statement from the institution or supervisor is accepted. As a prerequisite for a PhD fellowship employment, your master’s degree must be equivalent to a Danish master’s degree. We encourage you to read more in the assessment database: https://ufm.dk/en/education/recognition-and-transparency/find-assessments/assessment-database. Please note that we might ask you to obtain an assessment of your education performed by the Ministry of Higher Education and Science.
4. Publication list (if possible)

Application deadline: 8 June 2023 23.59pm CET
We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.

The further process
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor.
The assessor makes a non-prioritized assessment of the academic qualifications and experience with respect to the above-mentioned area of research, techniques, skills and other requirements listed in the advertisement.
Once the assessment work has been completed each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.

You find information about the recruitment process at: http://employment.ku.dk/faculty/recruitment-process/

The applicants will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.

Interviews are expected to be held in week 25.

The University of Copenhagen wish to reflect the diversity of society and encourage all qualified candidates to apply regardless of personal background.

INFORMATIONER OM STILLINGEN:

- Arbejdspladsen ligger i:

Glostrup Kommune

-Virksomheden tilbyder:

-Arbejdsgiver:

KU - SCIENCE BIO - BRIC, Ole Maaløes Vej 5, 2200 København N

-Ansøgning:

Ansøgningsfrist: 08-06-2023; - ansøgningsfristen er overskredet

Ved skriftlig henvendelse: https://candidate.hr-manager.net/ApplicationInit.aspx?cid=1307&ProjectId=159356&DepartmentId=19025&MediaId=4632&SkipAdvertisement=true

Se mere her: https://job.jobnet.dk/CV/FindWork/Details/5840724

Denne artikel er skrevet af Emilie Bjergegaard og data er automatisk hentet fra eksterne kilder, herunder JobNet.
Kilde: JobNet